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Could synNotch CAR T cells be the answer to fighting solid tumours? – Drug Target Review

Researchers have developed a novel CAR T-cell therapy for neuroblastoma which uses gating to limit toxicity and T-cell exhaustion.

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Posted: 22 January 2021 | Hannah Balfour (Drug Target Review) | No comments yet
Researchers have developed a novel CAR T-cell therapy for neuroblastoma which uses gating to limit toxicity and T-cell exhaustion.
A novel chimeric antigen receptor T-cell (CAR T) therapy targeting neuroblastoma effectively killed cancer cells while sparing healthy tissues in pre-clinical studies. While this work is in the preclinical phase, the developers of the treatment said it opens the door for other potentially…

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