Science
Computational model could improve success in translating drugs from animal studies to humans – Mirage News
Doug Brubaker, a Purdue assistant professor of biomedical engineering, uses computational and experimental approaches to study host-microbiome…
WEST LAFAYETTE, Ind. — About 50% of people who take the drug infliximab for inflammatory bowel diseases, such as Crohn’s disease, end up becoming resistant or unresponsive to it.
Scientists might be able to catch problems like this one earlier in the drug development process, when drugs move from testing in animals to clinical trials, with a new computational model developed by researchers from Purdue University and Massachusetts Institute of Technology.
The researchers call the model “TransCo…
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