Health
‘Bystander’ cytosines meet their match in gene-editing technique – Phys.org
Biomolecular engineers at Rice University have found a C-worthy technique that dramatically enhances the accuracy of gene editing.
Biomolecular engineers at Rice University have found a C-worthy technique that dramatically enhances the accuracy of gene editing.
The Rice lab of biomolecular engineer Xue Sherry Gao has introduced a set of tools that increase the accuracy of CRISPR-based edits in disease sequence models up to 6,000-fold compared with a current base editor, BE4max, that is considered state-of-the-art.
The work appears in the open-access journal Science Advances.
Cytosine base editors are able to convert cyto…
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