Health
Breast cancer–secreted factors perturb murine bone growth in regions prone to metastasis – Science Advances
Breast cancer frequently metastasizes to bone, causing osteolytic lesions. However, how factors secreted by primary tumors affect the bone microenvironment before…
INTRODUCTION
Bone metastasis is a leading cause of morbidity and mortality in patients with advanced breast cancer (1, 2). Nevertheless, therapeutic strategies to prevent bone metastasis are lacking, due, in part, to limited understanding of the mechanisms that enable breast cancer cells to seed and eventually develop secondary tumors in the skeleton. Disseminated tumor cells (DTCs) that have spread from the primary breast tumor to bone can colonize early in tumorigenesis (3). This process is potentially…
-
Noosa News23 hours agoParkyn this, Parkyn that | Noosa Today
-
Noosa News21 hours agoDog daycare program a TikTok hit for helping disabled find work, friends
-
Noosa News21 hours agoAdvocates highlight sexual violence against older people, with Queensland elder abuse inquiry underway
-
Business19 hours ago3 steps to take to build a $1,000 monthly passive income