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Blocking cellular communication stops SARS-CoV-2 – EurekAlert

Many viruses use and manipulate the communication pathways of their host cells to boost their own replication. Now biochemists and virologists from Goethe University and University Hospital Frankfurt have drawn a complete picture of communication within human…

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In the transmission of signals within the cell which, for example, stimulate cell growth or trigger metabolic processes, phosphate groups play an important biochemical role. The phosphate groups are often attached to proteins or removed to control activity. In this process, a change in the protein triggers the next one and the signal is transmitted in a signaling cascade. The target is usually the cell nucleus, where genes are switched on or off.
For the first time, biochemists and virologists …

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