Health
Bispecific IgG switch off SARS-CoV-2 escape variants – European Biotechnology News
A bispecific antibody designed by a Swiss-Czech research team suppressed viral escape of SARS-CoV-2 variants in animals.
A bispecific antibody designed by a Swiss-Czech research team suppressed viral escape of SARS-CoV-2 variants in animals. The team headed by Daniel Ruzek or Luca Varani from the University of Bellinzona and the Czech Academy of Sciences targeted two binding sites within the receptor binding domain (RBD) of the SARS-CoV-2 Spike (S) protein to prevent generation of viral survivors. The engineered bispecific, IgG1-like molecule (CoV-X2) based on two antibodies derived from COVID-19 convalescent donors,…
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