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Biomarkers that are predictive of clinical benefit in Trop-2-expressing triple-negative breast cancer – News-Medical.Net
Oncotarget recently published “Predictive biomarkers for sacituzumab govitecan efficacy in Trop-2-expressing triple-negative breast cancer” which reported that…
Reviewed by Emily Henderson, B.Sc.Nov 3 2020
Oncotarget recently published “Predictive biomarkers for sacituzumab govitecan efficacy in Trop-2-expressing triple-negative breast cancer” which reported that the authors investigated whether Trop-2-expression and homologous recombination repair of SN-38-mediated double-strand DNA breaks play a role in the sensitivity of triple-negative breast cancer to SG.
Further, two Trop-2-transfectants of MDA-MB-231, C13, and C39, were treated in mice with SG to…
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