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Biocompatible photooxygenation catalyst could be potentially used to treat amyloid diseases – News-Medical.Net

A new, biocompatible photooxygenation catalyst that can selectively oxygenate and degrade the pathogenic aggregation of Alzheimer’s disease (AD)-related amyloid-β…

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Reviewed by Emily Henderson, B.Sc.Nov 25 2020
A new, biocompatible photooxygenation catalyst that can selectively oxygenate and degrade the pathogenic aggregation of Alzheimer’s disease (AD)-related amyloid-β peptide (Aβ) under near-infrared (NIR) light irradiation is developed.
The catalyst was able to oxygenate Aβ embedded under the skin of a living mouse, and diminished intact Aβ level in AD-model mouse brain. The new catalyst is potentially applicable for the treatment of peripheral amyloid…

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