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Back to Normal; Serological Testing for COVID‐19 Diagnosis Unveils Missed Infections – Wiley

BackgroundThe gold standard for coronavirus disease (COVID‐19) diagnosis has been the detection of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)…

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Background
The gold standard for coronavirus disease (COVID19) diagnosis has been the detection of severe acute respiratory syndrome coronavirus 2 (SARSCoV2) RNA by nucleic acid amplification testing (NAAT). On the other hand, serological testing for COVID19 may offer advantages in detecting possibly overlooked infections by NAAT.
Methods
To evaluate seroconversion of NAATnegative pneumonia patients, IgM and IgG targeting the spike protein of SARSCoV2 were semiquantified by an immunofluorescence…

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