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Aspirin vs. ibuprofen: The key differences and which one you should take – Insider – INSIDER

Aspirin and ibuprofen are both anti-inflammatory drugs used to treat pain, inflammation, and fever — though they have some key differences.

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If you’ve taken an over-the-counter pain reliever before, you’ve likely had aspirin or ibuprofen. These are both very common nonsteroidal anti-inflammatory drugs, or NSAIDs, that are typically used to treat pain, inflammation, and fevers. 
They are popular active ingredients in various brand name products such as Advil and Motrin (ibuprofen) or Bayer and Ecotrin (aspirin). However, just because they are over-the-counter, it doesn’t mean that they come without risks or are safe for everyone to use. 

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