Antibody-like proteins that capture and neutralize SARS-CoV-2 – AlKhaleej Today

In order to combat the coronavirus 2 (SARS-CoV-2) associated with acute respiratory syndrome and unknown emerging pathogens in the future, the development of a fast and effective method for the generation of high-affinity antibodies or antibody-like proteins is of crucial importance. We report here on a high-speed in vitro selection of several high-affinity antibody-like proteins against various targets, including the SARS-CoV-2 spike protein. The sequences of monobodies against the SARS-CoV-2 s…

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