Health
Animal tests reveal synthetic decoy protein protects against coronavirus – Chemistry World
Protein designed from scratch binds Sars-CoV-2 with high affinity and specificity
While Pfizer and Moderna request emergency approvals for their coronavirus vaccines, researchers in Hong Kong and the US have discovered a new weapon that could fight the virus. Combining de novo design and directed evolution, they created a protein that binds to Sars-CoV-2 spike protein, blocking its infection pathway. The protein neutralises the virus in vitroand shows promising results in hamsters, protecting them from coronavirus infection after a small intranasal dose.
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