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Ancient part of immune system may underpin severe COVID – Science Daily

New genetic and patient analyses suggest severe COVID is linked to overactive complement, one of the immune system’s oldest branches, and excess blood clotting.

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One of the immune system’s oldest branches, called complement, may be influencing the severity of COVID disease, according to a new study from researchers at Columbia University Irving Medical Center.Among other findings linking complement to COVID, the researchers found that people with age-related macular degeneration — a disorder caused by overactive complement — are at greater risk of developing severe complications and dying from COVID.
The connection with complement suggests that existi…

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