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A step closer to gene therapy that restores hearing for congenitally deaf – Health Europa

Findings from a new study have brought the possibility of gene therapy that could restore hearing in the congenitally deaf one step closer.

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Mutations in the inner-ear protein coding gene otoferlin are linked to severe congenital hearing loss, however, the gene is too big to package into a delivery vehicle for molecular therapy. Now, a team of researchers from Oregon State University is exploring using otoferlin in a shortened form to use for this therapy.
The findings have been published today in Molecular Biology of the Cell.
Gene mutations
Associate professor of biochemistry and biophysics in the OSU College of Science, Colin Johnson,…

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