A large-scale tool to investigate the function of autism spectrum disorder genes – Devdiscourse

Scientists at Harvard University, the Broad Institute of MIT and Harvard, and MIT have developed a technology to investigate the function of many different genes in many different cell types at once, in a living organism. They applied the large-scale method to study dozens of genes that are associated with autism spectrum disorder, identifying how specific cell types in the developing mouse brain are impacted by mutations.
The “Perturb-Seq” method, published in the journal Science, is an efficient…

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