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A dance of histones silences transposable elements in pluripotent stem cells – EurekAlert
A study lead by SciLifeLab Fellow Simon Elsässer elucidates the mechanism of a peculiar type of heterochromatin, used by embryonic stem cells to silence ‘parasi…
IMAGE: The mechanism of a peculiar type of heterochromatin, used by embryonic stem cells to silence ‘parasitic’ DNA-elements within the context of their highly dynamic pluripotent chromatin.
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Credit: Simon Elsässer
So-called transposons are abundant DNA-elements found in every eukaryotic organism as a consequence of their ability to jump and multiply within the host genome. Their activity represents a threat to the integrity of the host genome and thus the host cell engages a numbe…
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