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Investigational Drug Stops Toxic Proteins Tied to Neurodegenerative Diseases – Mirage News
PHILADELPHIA — An investigational drug that targets an instigator of the TDP-43 protein, a well-known hallmark of amyotrophic lateral sclerosis (ALS) and…

PHILADELPHIA — An investigational drug that targets an instigator of the TDP-43 protein, a well-known hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), may reduce the protein’s buildup and neurological decline associated with these disorders, suggests a pre-clinical study from researchers at Penn Medicine and Mayo Clinic. Results were published in Science Translational Medicine.
The work shows, for the first time, how toxic poly(GR) (glycine-arginine repeat) pro…
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