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Coronacept – A trap-and-destroy molecule against SARS-CoV-2 – News-Medical.Net

A new study published on the preprint server bioRxiv* in August 2020 reports a novel engineered molecule based on human and other mammalian orthologues of ACE2 fused with the Fc part of the antibody. This molecule interacts more tightly with the viral recepto…

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The current pandemic of COVID-19 is due to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which enters the human host cell via the receptor molecule called the angiotensin-converting enzyme 2 (ACE2). A new study published on the preprint server bioRxiv* in August 2020 reports a novel engineered molecule based on human and other mammalian orthologues of ACE2 fused with the Fc part of the antibody. This molecule interacts more tightly with the viral receptor-binding domain (RBD) …

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