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Prostate cancer metastasis linked to revival of dormant molecular program – Medical Xpress

When prostate cancer progresses to a more-dangerous metastatic state, it does so by resurrecting dormant molecular mechanisms that had guided the fetal development of the prostate gland but had been subsequently switched off, say scientists from Dana-Farber C…

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When prostate cancer progresses to a more-dangerous metastatic state, it does so by resurrecting dormant molecular mechanisms that had guided the fetal development of the prostate gland but had been subsequently switched off, say scientists from Dana-Farber Cancer Institute.
The study, an international collaboration with The Netherlands Cancer Institute, was published in Nature Genetics. “It shows that particular programs that were operative during prostate fetal development become reactivated …

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