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NASH limits anti-tumour surveillance in immunotherapy-treated HCC – Nature.com
In hepatocellular carcinoma driven by non-alcoholic steatohepatitis, aberrant T cell activation and impaired immune surveillance seem to make hepatocellular carcinoma…
Mice, diets, and treatments
Standard mouse diet feeding (ad libitum water and food access) and treatment regimens were as described previously17. Male mice were housed at the German Cancer Research Center (DKFZ) (constant temperature of 2024°C and 4565% humidity with a 12-h lightdark cycle). Mice were maintained under specific pathogen-free conditions and experiments were performed in accordance with German law and the governmental bodies, and with approval from the Regierungspräsidium Karlsruhe…
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