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Scientists achieve milestone in animal-free production of biologics – The Science Board

For the first time, scientists have successfully produced sugar-based biologic molecules utilizing bacteria, without the need for animal products. The paper, published…

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Sulfated glycosaminoglycans (GAGs) are linear polysaccharides consisting of repeating disaccharide units composed of N-acetylhexosamine and uronic acid. They are ubiquitously distributed on the cell surface and in the extracellular matrix. GAGs play a role in a variety of cellular functions including cell to cell and cell to matrix adhesion, cell proliferation, cell division, morphogenesis, and the regulation of signaling molecules.
Two of the most used GAGs are heparin and CS. Heparin is the main…

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