Disrupting cancer cell cycle with two commercially available inhibitors causes tumor cell death – News-Medical.net

With two commercially available inhibitors, the cell cycle of the cancer cells in the childhood tumor neuroblastoma can be disrupted at a key point causing tumor cell death.
Neuroblastomas are malignant solid tumors that occur mainly in early childhood. They arise from degenerated immature cells of the sympathetic nervous system.
One prognostic marker to assess the malignancy of the tumor is the MYCN oncogene. High-risk neuroblastoma patients often have amplification of MYCN, i.e. very high levels…

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