Rules of resistance against transgene silencing – Phys.org

Clear rules for engineering transgenes that can be inserted and propagated over multiple generations of nematodes include ways to protect inserted genes from the organism’s natural defenses against foreign DNA. Developed by KAUST researchers, the rules have implications for many research fields, including gene therapy development.
Scientists often study biological processes, such as normal and mutant gene functions, in the worm Caenorhabditis elegans because it has many genes and molecular pathways…

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