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Dementia Tied to Large Perivascular Spaces – MedPage Today
Enlarged spaces around cerebral small blood vessels linked to cognitive decline over time

Enlarged fluid-filled spaces around cerebral small blood vessels were linked to cognitive decline, a prospective study of older adults showed.
Severe perivascular space pathology in both the basal ganglia and the centrum semiovale, or in the centrum semiovale alone, was tied to a greater drop in global cognition over 4 years, reported Matthew Paradise, MBChB, MSc, of the University of New South Wales in Sydney, Australia, and co-authors.
Large perivascular space dilation in both brain regions was…
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