Modified version of CAR T-cell therapy shows promise in targeting neuroblastoma – News-Medical.Net

Chimeric Antigen Receptor T-cell therapy–CAR T–has revolutionized leukemia treatment. Unfortunately, the therapy has not been effective for treating solid tumors including childhood cancers such as neuroblastoma. Preclinical studies using certain CAR T against neuroblastoma revealed toxic effects.
Now, a group of scientists at Children’s Hospital Los Angeles have developed a modified version of CAR T that shows promise in targeting neuroblastoma, spares healthy brain tissue and more effectively…

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