Health
New statistical method exponentially increases ability to discover genetic insights – EurekAlert
A test of the Sum-Share statistical method with only summary-level data found 1,734 genetic variations associated with cardiovascular-related conditions when just…
Pleiotropy analysis, which provides insight on how individual genes result in multiple characteristics, has become increasingly valuable as medicine continues to lean into mining genetics to inform disease treatments. Privacy stipulations, though, make it difficult to perform comprehensive pleiotropy analysis because individual patient data often can’t be easily and regularly shared between sites. However, a statistical method called Sum-Share, developed at Penn Medicine, can pull summary information…
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