Health
Scientists create ON-OFF switches to control CAR T cell activity – Medical Xpress
Scientists at Dana-Farber Cancer Institute and Mass General Cancer Center have created molecular ON-OFF switches to regulate the activity of CAR T cells, a potent…
Scientists at Dana-Farber Cancer Institute and Mass General Cancer Center have created molecular ON-OFF switches to regulate the activity of CAR T cells, a potent form of cell-based immunotherapy that has had dramatic success in treating some advanced cancers, but which pose a significant risk of toxic side effects.
CAR T cells are immune cells genetically modified to recognize and attack tumors cells. Once given, these “living drugs” proliferate and kill tumor cells over weeks to months, in some…
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