Researchers identify adenovirus gene therapy for placental insufficiency – News-Medical.Net

A new study identified an adenovirus gene therapy vector carrying a VEGF isoform. It can improve uterine blood flow in placental insufficiency, as reported in the peer-reviewed journal Human Gene Therapy.
Reduced uterine blood flow and lack of bioavailable VEGF due to placental insufficiency is a major cause of severe fetal growth restriction (FGR). This is untreatable and causes serious neonatal morbidity and death.
Anna David, UCL Institute for Women’s Health, and colleagues tested different VEGF…

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