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Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms – Science Magazine

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is closely related to the deadly coronaviruses SARS-CoV-1 and Middle East respiratory syndrome coronavirus…

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In the past two decades, three deadly human respiratory syndromes associated with coronavirus (CoV) infections have emerged: severe acute respiratory syndrome (SARS) in 2002, Middle East respiratory syndrome (MERS) in 2012, and COVID-19 in 2019. These three diseases are caused by the zoonotic coronaviruses severe acute respiratory syndrome coronavirus 1 (SARS-CoV-1), Middle East respiratory syndrome coronavirus (MERS-CoV), and SARS-CoV-2 (1), respectively. Before their emergence, human coronaviruses…

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