Health
Novel targeted therapy blocks metabolic pathways in cancer cells with specific genetic defects – News-Medical.Net
Researchers at The University of Texas MD Anderson Cancer Center have developed a novel targeted therapy, called POMHEX, which blocks critical metabolic pathways…
Reviewed by Emily Henderson, B.Sc.Nov 23 2020
Researchers at The University of Texas MD Anderson Cancer Center have developed a novel targeted therapy, called POMHEX, which blocks critical metabolic pathways in cancer cells with specific genetic defects. Preclinical studies found the small-molecule enolase inhibitor to be effective in killing brain cancer cells that were missing ENO1, one of two genes encoding the enolase enzyme.
The study results, published today in Nature Metabolism, provide proof…
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