Health
Enhancing host cell infection by SARS-CoV-2 – Science Magazine
The current global pandemic of coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A critical initial…
The current global pandemic of coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A critical initial step of infection is the interaction of the virus with receptors on host cells. In the case of SARS-CoV-2 and other coronaviruses, this receptor binding occurs through the spike (S) protein on the virus surface. Both SARS-CoV-2 and the related SARS-CoV, which caused an outbreak in 2003, bind to angiotensin-converting enzyme 2 (ACE2) on human…
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