Health
Researchers develop ACE2 decoy to neutralise SARS-CoV-2 – Drug Target Review
Researchers have engineered human angiotensin converting enzyme 2 (hACE2) protein decoys that can protect cells from SARS-CoV-2.
Posted: 10 November 2020 | Hannah Balfour (Drug Target Review) | No comments yet
Using their de novo protein design strategy, researchers engineered human angiotensin converting enzyme 2 (hACE2) protein decoys that can protect cells from SARS-CoV-2 infection.
To infect cells within the respiratory tract, the Spike (S) protein on the surface of SARS-CoV-2 must bind to a receptor on human cells called angiotensin converting enzyme 2 (ACE2). The receptor binding domains (RBDs) are the section of the…
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