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Enzyme biofactories to enhance cord blood transplants – EurekAlert

Stem cell trafficking to the bone marrow is improved by enzyme manufactured in silkworms and yeast.

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IMAGE: The researchers showed that their yeast- and silkworm-derived enzyme far outperformed commercial sources of the enzyme made in standard expression systems.
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Credit: © 2020 KAUST; Heno Hwang
A new way of producing an enzyme called fucosyltransferase VI (FTVI) in the lab could help enhance the therapeutic potential of cord blood transplants.
Cord blood is currently used to treat more than 80 life-threatening conditions, ranging from cancer and immune deficiency to metabolic and genetic…

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