Unconventional T cell subset enriched in airways of some patients with severe COVID-19 – Science Codex

Unconventional T cells called mucosa-associated invariant T (MAIT) cells are recruited to the airways and strongly activated in some patients with severe COVID-19, a new study has found, suggesting the cells’ possible involvement in the development of disease. These findings corroborate other recent studies that highlight potential associations between strong MAIT cell activation and severe COVID-19 outcomes. MAIT cells, representing 1% to 10% of T cells in the blood, can readily home into speci…

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