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Imaging probe to visualize Alzheimer’s disease-related gamma-secretase in the brain – EurekAlert
Scientists have developed a molecular imaging probe to reveal Alzheimer’s-related γ-secretase in rodents and macaques with translational potentials in humans
BOSTON – Scientists at the Massachusetts General Hospital (MGH) have developed a molecular imaging probe to reveal Alzheimer’s disease (AD)-related γ-secretase in rodents and macaques with translational potentials in humans. γ-Secretase is a key player in the etiology of AD and a prime drug target for AD, whose brain regional expression and distribution have yet remain largely unknown. This study describes the development of a molecular imaging probe to reveal γ-secretase in rodents and macaques…
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