Science
Detection of PCBs and their metabolites (OH-PCBs) in the fetal brain of a Japanese macaque – EurekAlert
This study selected the Japanese macaque (Macaca fuscata) as a model animal for the fetal transfer of OH-PCBs in humans, and revealed OH-PCB concentrations and their relationships in the maternal and fetal brains. The key finding from this study is that OH-PC…
IMAGE: Concentrations (pg g?1) of OH-PCBs in the brain, liver, and placenta of a Japanese macaque fetus.
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Credit: Center for Marine Environmental Studies (CMES), Ehime University
Hydroxylated polychlorinated biphenyls (OH-PCBs) are metabolites of PCBs and known endocrine disruptors in humans. Of particular concern regarding this kind of effect has been the disruption of the thyroid hormone homeostasis by OH-PCBs. Some OH-PCB congeners are involved in disrupting TH transport by comp…
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