Science
The custom transcriptome – Science Magazine
The panorama of human phenotypes arises from a mix of common and rare genetic variants, some of which affect how genes are expressed and spliced throughout the body. More than a decade ago, scientists aiming to better understand the effects of genetic diversi…

Heatmaps of differential gene expression among individuals from the Genotype-Tissue Expression Project. From left to right, illustrations represent data obtained for the lungs, heart, intestines, and thyroid.
ILLUSTRATION: V. ALTOUNIAN/SCIENCE, IN COLLABORATION WITH CHRISTIAN STOLTE; (DATA) GTEX CONSORTIUM
The panorama of human phenotypes arises from a mix of common and rare genetic variants, some of which affect how genes are expressed and spliced throughout the body. More than a decade ago, …