Health
Norovirus strains differ in sensitivity to body’s first line of defense – Mirage News
Interferon (IFN) responses are one of the first defenses the body mounts against viral infections, and research has shown that it plays a role…
Interferon (IFN) responses are one of the first defenses the body mounts against viral infections, and research has shown that it plays a role controlling viral replication. But when researchers at Baylor College of Medicine investigated whether IFN restricted human norovirus (HuNoV) infection in human intestinal enteroids (HIEs), a cultivation system that recapitulates many of the characteristics of the human infection, they unexpectedly discovered that endogenous IFN responses by HIEs restrict…
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