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Stomach SIDT1 mediates dietary microRNA absorption – Phys.org

In a new study published in Cell Research, Chen-Yu Zhang’s group at Nanjing University School of Life Sciences, China, reports that SIDT1 in the mammalian stomach mediates host uptake of dietary and orally administered microRNAs (miRNAs), thus exerting biolog…

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In a new study published in Cell Research, Chen-Yu Zhang’s group at Nanjing University School of Life Sciences, China, reports that SIDT1 in the mammalian stomach mediates host uptake of dietary and orally administered microRNAs (miRNAs), thus exerting biological functions in the host.
In previous studies, Chen-Yu Zhang’s group has demonstrated that intact plant miRNA in foods can be absorbed through the mammalian digestive system and mediate cross-kingdom gene regulation. The discoveries also …

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