Health
Silencing the SARS-CoV-2 Receptor With CRISPR and Epigenetic Modifications – Technology Networks
What happens when you transiently turn “off” the gene that encodes ACE2, the protein that is required for SARS-CoV-2 to enter and infect cells? This is what Jamie Hackett and colleagues are currently exploring in animal models, to determine whether epigenetic…
The Hackett Group at EMBL Rome explores epigenetics, genome regulation and cell identity. Recently, the scientists developed a novel CRISPR molecular tool for editing the epigenome, enabling transient modifications that can switch certain genes “on” and “off” temporarily.The SARS-CoV-2 virus that has caused the COVID-19 global pandemic makes its way into a host cell via a protein known as ACE2, which is involved in a range of physiological functions in the body.
What happens when you transientl…
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