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Research offers clues on why pregnancy may raise risk of organ transplant rejection – News-Medical.Net

A research study at the University of Chicago has found that in pregnancy, while the T cell response to a fetus becomes tolerant to allow for successful pregnancy,…

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A research study at the University of Chicago has found that in pregnancy, while the T cell response to a fetus becomes tolerant to allow for successful pregnancy, the part of the immune system that produces antibodies (known as the humoral response) becomes sensitized, creating memory B cells that can later contribute to the rejection of a transplanted organ.
The results help to clarify why it is that the immune system can tolerate a fetus during pregnancy, but later may be more likely to become…

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