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Protein alteration contributes to degeneration of neuronal populations in Huntington’s disease – News-Medical.net

Protein alteration in the family of lamins causes several diseases, known as laminopathies, such as progeria or precocious aging.

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Protein alteration in the family of lamins causes several diseases, known as laminopathies, such as progeria or precocious aging.
A study in which UB researchers have taken part states that alterations in the levels of one of these proteins, lamin B1, contribute to the degeneration of different brain neuronal populations in Huntington’s disease. Caused by a mutation in the huntingtin gene, this pathology features involuntary movements, cognitive deficit, and psychiatric disorders, and has no cure…

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