Science
Only Two Interchangeable Ways to Fold Genomes into Nuclei – Genetic Engineering & Biotechnology News
Scientists have mapped 3D genome organization at a chromosomal level in 24 eukaryotic species, including animals, fungi, and plants, and concluded there are only…
Precisely how genomes ranging from a few million to billion base-pairs, several meters long, can fold into minuscule cellular nuclei, on average 6 microns in size, is a baffling conundrum. Yet, chromosome-level nuclear architecture, though poorly understood can play a crucial role in regulating gene expression in health and disease.
A new collaborative study investigates the principles of genome folding across the eukaryotic tree of life including 24 species, representing all taxonomic groups in…
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