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Molecular imaging probe reveals Alzheimer’s-related γ-secretase in rodents, macaques – News-Medical.Net

Scientists at the Massachusetts General Hospital (MGH) have developed a molecular imaging probe to reveal Alzheimer’s disease (AD)-related γ-secretase in rodents and macaques with translational potentials in humans.

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Reviewed by Emily Henderson, B.Sc.Sep 18 2020
Scientists at the Massachusetts General Hospital (MGH) have developed a molecular imaging probe to reveal Alzheimer’s disease (AD)-related γ-secretase in rodents and macaques with translational potentials in humans. γ-Secretase is a key player in the etiology of AD and a prime drug target for AD, whose brain regional expression and distribution have yet remained largely unknown.
This study describes the development of a molecular imaging probe to r…

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