Health
AACR: MD Anderson team uncovers new target for blocking mutant KRAS and p53 in pancreatic cancer – FierceBiotech
An MD Anderson team discovered that mutant KRAS and p53 rely on a protein called CREB1 to drive the growth and spread of pancreatic cancer. Blocking CREB1 in mouse…
Mutations in the genes KRAS and p53 have been tied to several tumor types, including pancreatic cancer. Scientists at the University of Texas MD Anderson Cancer Center say they have found a critical link between the two abnormal genes and tumor growth in pancreatic cancerand theyre proposing a way to block it.
The MD Anderson team discovered that mutant KRAS and p53 rely on a protein called CREB1 to drive the growth and spread of pancreatic cancer. Blocking CREB1 in mouse models of the disease reduced…
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