Health
Researchers identify antibodies that prevent SARS-CoV-2 from infecting human cells – News-Medical.Net
The ability of SARS-CoV-2 to infect cells depends on interactions between the viral spike protein and the human cell surface protein ACE2.
Reviewed by Emily Henderson, B.Sc.Nov 5 2020
The ability of SARS-CoV-2 to infect cells depends on interactions between the viral spike protein and the human cell surface protein ACE2.
To enable the virus to hook onto the cell surface, the spike protein binds ACE2 using three finger-like protrusions, called the receptor binding domains (RBDs). Blocking the RBDs therefore has the potential to stop the virus from entering human cells. This can be done using antibodies.
Nanobodies, small antibodies…
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